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https://hdl.handle.net/20.500.12411/670| Title: | Analytical method validation for metformin quantification in dissolution medium |
| Authors: | Bogantes-Molina, Joselyn Madrigal-Redondo, German Leonardo Berrocal-Barrantes, Lorena Chavarría-Rojas, Marianela Acuña-Amador, Daniel Alejandro Vargas-Zúñiga, Rolando |
| Keywords: | metformin hydrochloride validation analytical method quantification dissolution spectrophotometry |
| Publisher: | GSC Biological and Pharmaceutical Sciences |
| Citation: | Bogantes-Molina, J., Madrigal-Redondo, G. L., Berrocal-Barrantes, L., Chavarría-Rojas, M., Acuña-Amador, D. A., y Vargas-Zúñiga, R. (2019). Analytical method validation for metformin quantification in dissolution medium. GSC Biological and Pharmaceutical Sciences, 7(2), 43-51. https://doi.org/10.30574/gscbps.2019.7.2.0049 |
| Abstract: | Metformin hydrochloride is a hypoglycemic agent used for type II Diabetes Mellitus treatment, and one of the most used to manage it. The objective of the present work was the development and validation of an analytical method to quantify metformin hydrochloride in the dissolution medium by UV spectrophotometry. Linearity and range, accuracy and precision were the validation process parameters. Validation process results showed the analytical method was easy, quick, secure and, furthermore, a linear, accurate and precise method in the studied concentrations range. Therefore, it is a reliable analytical method. |
| URI: | https://doi.org/10.30574/gscbps.2019.7.2.0049 https://hdl.handle.net/20.500.12411/670 |
| Appears in Collections: | Artículos publicados en revistas internacionales |
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